£20m boost for research into the developing brain

March 7th, 2017

The Simons Foundation has pledged £20 million for pioneering studies into the biological mechanisms that underpin changes in brain development associated with autism. The Simons Initiative for the Developing Brain will be based at the Patrick Wild Centre. “This is an amazing opportunity to bring together a range of scientific and clinical expertise at the University with the aim of understanding how the brain develops on multiple levels, including molecular biology, neural circuitry, genetics, behaviour and cognition. By combining these …

Paper published in Journal of Neurochemistry

January 12th, 2017

Dr Emily Osterweil, a Chancellors Fellow at the Patrick Wild Centre and Dr Susana Louros have recently had a paper published in the Journal of Neurochemistry titled; Perturbed proteostasis in autism spectrum disorders. Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes encoding regulators of mRNA translation and members of …

Family in Residence: Videos from our Family

January 12th, 2017

For our Family in Residence Project we have put together a series of  2 to 3 minute videos in which the Mcdonalds talk about family life, Stuart and Matthews education, the support from the community and their experiences with Fragile X Syndrome. These videos will be shared across our community with teachers, schools and supporters to aid with teaching, understanding and raising awareness of Fragile X Syndrome. Diagnosis: Gillian and Craig Mcdonald talk about diagnosis of Stuart and Matthew with Fragile X Syndrome …