Clinical Trials

Advances in our understanding of the mechanisms behind neurodevelopmental disorders are beginning to lead to the development of new treatments for these conditions.

The strong links between the University of Edinburgh and the NHS mean that the Patrick Wild Centre is ideally placed to undertake clinical trials of these new treatments. In addition to their research roles, the clinical academics at the Patrick Wild Centre also work within the NHS in services which include learning disability psychiatry, clinical genetics, specialist autism consultancy services and general psychiatry.

Ongoing Treatment Trials

A randomized, double blind, 12 week, parallel group, placebo controlled study of the efficacy and safety of RO4917523 in patients with Fragile X Syndrome

ClinicalTrials.gov Identifier: NCT01517698

This international multi-centre trial, run by Roche, aims to evaluate a new medication, RO4917523, for people aged 16-50 with Fragile X Syndrome. The Patrick Wild Centre is leading the research in the UK.  There are three Scottish sites (Lothian, Glasgow and Tayside) which are now recruiting and other UK sites are planned.

Please contact Dr Andrew Stanfield if you would like more details.

A randomised, double blind, randomised, placebo controlled, parallel-group study to evaluate AFQ056 in adult patients with Fragile X Syndrome

ClinicalTrials.gov Identifier: NCT01253629

This international multi-centre trial, run by Novartis, aims to evaluate a new medication, AFQ056, for adults (18-45 year olds) with Fragile X Syndrome.

Please check this page for progress updates.

A randomised, double blind, randomised, placebo controlled, parallel-group study to evaluate AFQ056 in adolescent patients with Fragile X Syndrome

ClinicalTrials.gov Identifier: NCT01357239

This international multi-centre trial, run by Novartis, aims to evaluate a new medication, AFQ056, for adolescents (12-17 year olds) with Fragile X Syndrome.

Please check this page for progress updates.

Both of these trials will begin in September 2011.  If you are interested in finding out more about them then please contact the Principal Investigator, Dr Andrew Stanfield.

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