Stephen Lawrie wins Public Communication prize

Many congratulations to Professor Stephen Lawrie of the Patrick Wild Centre, who has won the British Association for Psychopharmacology (BAP) Senior Public Communication Prize. The BAP Public Communication Prizes are awarded annually to reward excellence in both clinical and non-clinical science communication to the public in the area of psychopharmacology. Stephen won the prize for his many and varied public engagement contributions, including: ‘Mental health is…mental’ talk at the Cabaret of Dangerous Ideas, Edinburgh Festival Fringe August 2016 Radio 4 …

New paper from the Patrick Wild Centre

Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome. Sophie R. Thomson, Sang S. Seo, Stephanie A. Barnes,, Susana R. Louros, Melania Muscas, Owen Dando, Caoimhe Kirby, David J.A. Wyllie, Giles E. Hardingham, Peter C. Kind, Emily K. Osterweil. www.Osterlab.org The Osterweil lab has identified a potential new strategy for treating fragile x syndrome. As excessive protein synthesis is pathological in the fragile X brain, it is thought that over-produced proteins should be downregulated. In their study, they found that one …

Dr Sue Fletcher-Watson talks about autism on BBC5 live

Published

On 13 July 2017, Patrick Wild Centre Researcher Dr Sue Fletcher-Watson spoke to BBC Radio 5 Live about autism following an interview with best-selling author David Mitchell  about his autistic son.  Sue, along with Tom Purser (Head of Campaigns at the National Autistic Society and parent to an autistic son) and parent callers, spoke about changing perceptions of autism. You can listen to the interview here: BBC Radio 5 live (13july17 – from 36:20) – [available until 12aug17]  

The Family in Residence project has been nominated for the Thelmas

Published

The Family in Residence project has been nominated for the Times Higher Education Leadership and Management Awards 2017 in the category “Knowledge Exchange/Transfer Initiative of the Year”. The Family in Residence project, funded by the University of Edinburgh Innovation Initiative, has pioneered a new way to connect with stakeholders. Over 12 months the Patrick Wild Centre worked with a family, consisting of people with fragile X syndrome, carriers, and unaffected individuals, to be embedded within the Centre. During the year members …

Autism-linked condition helped by diabetes drug

A team of researchers led by Dr Christos Gkogkas from the Patrick Wild Centre, together with colleagues from McGill University and Université de Montréal, Canada, have found that a commonly used diabetes drug, Metformin, has the potential to help people with a common inherited form of autism (fragile X syndrome). Fragile X syndrome affects around 1 in 4,000 boys and 1 in 6,000 girls. It is the most common known cause of inherited intellectual disability. Affected children have developmental delays that impair …

4XTeam along the silk route

The 4XTeam – longstanding friends of The Patrick Wild Centre Gus Alusi and Reem Waines, along with their friends and family – have completed their newest adventure, which took Gus and friends along the silk route from London to Tashkent in just 17 days. The team took on a self-funded driving challenge to raise money for the Patrick Wild Centre. They were driving between eight to ten hours a day over very tough terrain. The journey covered approximately 7,000 miles …

Edinburgh March for Science

More than 2000 scientists and members of the public gathered in Edinburgh on the 22nd of April to promote and defend science. The March for Science saw them descend upon the Scottish Parliament, after starting their parade from Waterloo Place. The march ended with a series of speeches by academics. Professor Peter Kind, Co-Director of the Patrick Wild Centre, made a staunch defence of science. He said: “Our society needs and deserves a citizenry with minds wide awake and a …

£20m boost for research into the developing brain

The Simons Foundation has pledged £20 million for pioneering studies into the biological mechanisms that underpin changes in brain development associated with autism. The Simons Initiative for the Developing Brain will be based at the Patrick Wild Centre. “This is an amazing opportunity to bring together a range of scientific and clinical expertise at the University with the aim of understanding how the brain develops on multiple levels, including molecular biology, neural circuitry, genetics, behaviour and cognition. By combining these …

Paper published in Journal of Neurochemistry

Dr Emily Osterweil, a Chancellors Fellow at the Patrick Wild Centre and Dr Susana Louros have recently had a paper published in the Journal of Neurochemistry titled; Perturbed proteostasis in autism spectrum disorders. Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes encoding regulators of mRNA translation and members of …

Family in Residence: Videos from our Family

For our Family in Residence Project we have put together a series of  2 to 3 minute videos in which the Mcdonalds talk about family life, Stuart and Matthews education, the support from the community and their experiences with Fragile X Syndrome. These videos will be shared across our community with teachers, schools and supporters to aid with teaching, understanding and raising awareness of Fragile X Syndrome. Diagnosis: Gillian and Craig Mcdonald talk about diagnosis of Stuart and Matthew with Fragile X Syndrome …

Family In Residence: Life at Peebles High

We would like to share with you this short video shot by and starring Stuart and Matthew McDonald. The McDonald family came over to the Patrick Wild Centre as part of our Family In Residence Project, to record a series of videos that will aid with our future teaching. While we had the video cameras out, the boys took turns filming and interviewing each other. With graduation from high school looming, the conversation naturally turned to their school experience. We think the result shows …

Professor Adrian Bird awarded prize for research into Rett Syndrome

The Shaw Prize in Life Science and Medicine has been awarded to Adrian Bird, Buchanan Professor of Genetics, University of Edinburgh, UK for discovery of the genes and the encoded proteins that recognize one chemical modification of the DNA of chromosomes that influences gene control as the basis of the developmental disorder Rett syndrome. The Prize has been shared equally with  Huda Y Zoghbi  Professor of Pediatrics & Molecular and Human Genetics, Baylor College of Medicine, Director of Jan and Dan Duncan Neurological Research Institute, Texas …

Patrick Wild Centre researcher awarded prestigious fellowship to study potential new treatments for fragile X syndrome.

Dr Stephanie Barnes, a postdoctoral researcher in Dr Emily Osterweil’s lab at the Patrick Wild Centre, has been awarded a 2 year fellowship from FRAXA research organisation to test a potential new treatment strategy for fragile X syndrome. Stephanie will focus on a type of nerve signalling in the brain called NMDA receptor signalling which is known to be altered in fragile X syndrome.  She will test a novel treatment strategy to correct this signalling in a laboratory model of …

Celebrating Five Years of the Patrick Wild Centre with our #wildmiles Campaign.

Starting on April 16th 2016, and running for the next 12 months, we’re asking our centre members and supporters to go the extra mile to raise awareness of intellectual disabilities, autism and fragile x syndrome and our research into these. We’d like you to travel a mile under your own steam (walk, run, cycle swim, anything!), take a photo and share your wildmiles with us and the world via social media.  If possible, wearing orange, our centre colour. Watch the …

Patrick Wild Centre Symposium: Multi-Disciplinary Innovations in Developmental Science

On Tuesday the 1st March The Patrick Wild Centre together with the Salvesen Mindroom Centre, will be hosting Guest Speaker Professor Susan Gathercole, Director of the MRC Cognition and Brain Sciences Unit at Cambridge University. The symposium is a chance to bring together scientists with an interest in human development from across the University to hear about cutting edge research in the field. Speakers are drawn from medicine, psychology and education and will be talking about preterm birth, fragile X syndrome and visual …

Launch of the family in residence project at the Patrick Wild Centre

Together with our colleagues at DART (Developmental Autism Research Technology) we have won funding to host a ‘family in residence’ at the Patrick Wild Centre. The McDonalds will be invited to be involved in everything we do, from commenting on teaching to giving advice on future research plans. Craig McDonald has written a post to introduce his family and explain what this project means to them. Click here to read the full story.   Merken Merken

A trial of an iPad™ intervention targeting social communication skills in children with autism

Researchers of the Patrick Wild Centre investigated whether playing a specially-designed iPad™ game could help young children with autism develop basic social skills. They recruited 54 children aged under 6 years old who all had a diagnosis of autism, and they were randomly sorted into intervention (working with the iPad for 2 months) and control (no special support) groups. The game was enjoyed by the children and rated highly by parents – children played for about ten minutes per day …

World leader in FXS research visits the Patrick Wild Centre

Professor Jen Darnell of The Rockefeller University in the US, was one of two guest speakers to join us at a recent symposium. Jen is a leading authority on Fragile X Syndrome (FXS) – the most common cause of inherited intellectual disability. She had this to say about the Patrick Wild Centre: “I have been following the Centre since its inception and am very impressed by the quality of its research and its ability to bring together clinicians and fundamental researchers …

Our computer based working memory intervention is now looking for children and adults with Fragile X Syndrome

The Patrick Wild Centre will be running a pilot study for child and adults with fragile X syndrome, of an intervention called Cogmed.  Which  is a computer program  designed to improve a particular type of memory, called working memory. Research indicates that working memory may be an area of particular difficulty  for people with fragile X syndrome.   We hope that this study will be a step towards discovering whether interventions to improve working memory are useful or even possible in those with fragile X syndrome. The study is being  funded by …

New research at the Patrick Wild Centre to study men who carry the fragile X premutation

The Patrick Wild Centre is starting a new research project studying men who carry the fragile X premutation.  The study is open to recruitment now and more information about what it entails is available here. For this study we need to recruit both people with the premutation and a comparison group of men who do not carry the premutation.  So any man between the ages of 18 and 70 can take part! The study is funded by a research grant …

Patrick Wild Centre to study a memory based intervention for fragile X syndrome

The Patrick Wild Centre have recently been awarded funding to conduct a pilot study in people with fragile X syndrome of an intervention called Cogmed which is designed to improve a particular type of memory, called working memory. It is thought that working memory is particularly affected in people with fragile X syndrome, but it is not known whether interventions to improve working memory are useful or even possible in affected people.  We hope that this study will be a …

New University of Edinburgh research centre to investigate learning difficulties

Children and young people with learning difficulties are set to benefit from a new £5 million research and support centre at the University in association with the charity Mindroom. The Salvesen Mindroom Centre to Understand and Resolve Learning Difficulties will be the first of its kind in the UK. Funding for the virtual centre has been generously donated to the University by businessman and philanthropist Mr Alastair Salvesen, Chairman of Dawnfresh Seafoods Ltd, and his wife, Elizabeth. The Salvesen Mindroom …

Scottish Society of Architect Artists (SSAA) Art Exhibition in support of the Patrick Wild Centre

Art4X 21-24 January 2015 Scottish Society of Architect Artists (SSAA) Art Exhibition in support of the Patrick Wild Centre for Research into Autism, Fragile X Syndrome and Intellectual Disabilities. Exhibition details: 10.00am to 4.00pm on Wednesday 21 to Friday 23 January 2015 10.00am to 12 noon on Saturday 24 January 2015 Sculpture Hall Edinburgh College of Art The University of Edinburgh 74 Lauriston Place Edinburgh EH3 9D www.art4x.org.uk  

Patrick Wild Centre Supporters’ Day 24th November

This will take place on Monday 24th November 2014 at the Informatics Forum , 10 Crichton Street Edinburgh EH8 9AB from 2.30 – 4pm The afternoon will begin with a short presentation on the highlights of the past year. This will be followed with refreshments where you will have the opportunity to ask questions and share your thoughts about the Centre with us. Please email PWC_admin@ed.ac.uk or telephone 0131 537 6257 if you wish to attend.

Everest 4X have arrived at Base Camp

Gus Alusi and friends are currently trekking in the Everest region of Nepal to raise funds for the Patrick Wild Centre and we are pleased to say they have just made it safely to Base Camp.  Gus was instrumental in setting up the Patrick Wild Centre and we are very grateful to him and his friends for continuing to support us and raise awareness through their activities. You can follow the trek here and pledge your support here.   Merken

Scottish Mental Health Arts & Film Festival

The Scottish Mental Health Arts and Film Festival is one of Scotland’s most diverse cultural events, covering everything from music, film and visual art to theatre, dance, and literature. The annual festival will take place in venues across Scotland from the 1st – 19th October 2014, aiming to support the arts and challenge preconceived ideas about mental health.   http://www.mhfestival.com/