The CHANGES-SYNGAP1 study is a longitudinal study investigating behaviour and physiology in children, adolescents and adults with SYNGAP1-related disorder.  

We have now finished recruitment! In total, 24 individuals with SYNGAP1 (ages 3-24 years) and 17 typically developing controls (often SYNGAP1 siblings) took part. We measured behaviour, heart rate, pupil size and neural function. Currently, we are analysing the data and completing the collection of the final 1-year follow-up data sets.

Thanks to everyone who took part!